The cancellation rates tour and operators in Asia are seeing vary between 20 to 80 percent depending on their reliance on the Chinese market.
Construction of the theme park, the fifth such Universal Studios in the world, is expected to be completed by the end of 2020.
The epidemic is having a negative impact on Slender West Lake's $320 million asset-backed notes.
Indian tour operators estimate a $500 million loss because of cancellations from tourists from China and other countries.
The temporary closure of the two parks could result in a $175 million loss in Disney’s upcoming second quarter.
Tourism operations in mainland China account for 13% of the company's total operating revenue.
The national travel agency association urged Chinese travel agencies to fully understand and support "preferential terms to Chinese tourists to prevent the spread of the coronavirus pneumonia".
Disney said it would refund tickets for admission to Shanghai Disneyland or other services at the park as well as hotel bookings.